Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules

RIG-I triggers antiviral responses by recognizing viral RNA (vRNA) in the cytoplasm. However, the spatio-temporal dynamics of vRNA sensing and signal transduction remain elusive. We investigated the time course of events in cells infected with Newcastle disease virus (NDV), a non-segmented negative-...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Oh, Seong-Wook, Onomoto, Koji, Wakimoto, Mai, Onoguchi, Kazuhide, Ishidate, Fumiyoshi, Fujiwara, Takahiro, Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749238/
https://ncbi.nlm.nih.gov/pubmed/26862753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005444
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