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Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer

There is strong epidemiologic evidence linking chronic exposure to inorganic arsenic (iAs) to a myriad of adverse health effects, including cancer of the bladder. The present study set out to identify DNA methylation patterns associated with iAs and its metabolites in exfoliated urothelial cells (EU...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Rager, Julia E., Miller, Sloane, Tulenko, Samantha E., Smeester, Lisa, Ray, Paul D., Yosim, Andrew, Currier, Jenna M., Ishida, María C., González-Horta, Maria del Carmen, Sánchez-Ramírez, Blanca, Ballinas-Casarrubias, Lourdes, Gutiérrez-Torres, Daniela S., Drobná, Zuzana, Del Razo, Luz M., García-Vargas, Gonzalo G., Kim, William Y., Zhou, Yi-Hui, Wright, Fred A., Stýblo, Miroslav, Fry, Rebecca C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748849/
https://ncbi.nlm.nih.gov/pubmed/26039340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500393y
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