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Activating the branch-forming splicing pathway by reengineering the ribozyme component of a natural group II intron
When assayed in vitro, group IIC self-splicing introns, which target bacterial Rho-independent transcription terminators, generally fail to yield branched products during splicing despite their possessing a seemingly normal branchpoint. Starting with intron O.i.I1 from Oceanobacillus iheyensis, whos...
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| Publicado no: | RNA |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748821/ https://ncbi.nlm.nih.gov/pubmed/26769855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.054643.115 |
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