Successful Management of Crizotinib-Induced Neutropenia in a Patient with Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Case Report

Crizotinib, the first clinically available inhibitor of anaplastic lymphoma kinase (ALK) gene rearrangement, is generally well tolerated. In contrast, neutropenia induced by crizotinib is a commonly reported grade 3 or 4 adverse event. In such cases, interruption and dose reduction of crizotinib mig...

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Bibliografiske detaljer
Udgivet i:Case Rep Oncol
Main Authors: Osugi, Jun, Owada, Yuki, Yamaura, Takumi, Muto, Satoshi, Okabe, Naoyuki, Matsumura, Yuki, Higuchi, Mitsunori, Suzuki, Hiroyuki, Gotoh, Mitsukazu
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2016
Fag:
Published online: January, 2016
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748772/
https://ncbi.nlm.nih.gov/pubmed/26933419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000443662
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