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RRx-001-Induced Tumor Necrosis and Immune Cell Infiltration in an EGFR Mutation-Positive NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors: A Case Report

We present the case of a 49-year-old male with metastatic epidermal growth factor receptor (EGFR) mutation-positive adenocarcinoma of the lung that continues to outlive stage IV diagnosis of non-small cell lung cancer after treatment with RRx-001, an experimental anticancer agent with epigenetic and...

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Detalhes bibliográficos
Publicado no:Case Rep Oncol
Main Authors: Brzezniak, Christina, Schmitz, Bruno A., Peterson, Paul G., Degesys, Aiste, Oronsky, Bryan T., Scicinski, Jan J., Caroen, Scott Z., Carter, Corey A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748757/
https://ncbi.nlm.nih.gov/pubmed/26933418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000443605
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