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Primary and recurrent diffuse astrocytomas: genomic profile comparison reveals acquisition of biologically relevant aberrations

BACKGROUND: Diffuse astrocytomas are characterized by their highly variable biological behavior. The possibility that tumors develop novel aberrations, with relevant biological properties, is often neglected. In this study, we present two cases of diffuse astrocytoma in which additional cytogenetic...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Main Authors: Lhotska, Halka, Zemanova, Zuzana, Cechova, Hana, Ransdorfova, Sarka, Svobodova, Karla, Kramar, Filip, Krejcik, Zdenek, Michalova, Kyra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748601/
https://ncbi.nlm.nih.gov/pubmed/26865861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0222-3
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