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Identification of a nucleotide in 5′ untranslated region contributing to virus replication and virulence of Coxsackievirus A16

Coxsackievirus A16 (CA16) and enterovirus 71 (EV71) are two main causative pathogens of hand, foot and mouth disease (HFMD). Unlike EV71, virulence determinants of CA16, particularly within 5′ untranslated region (5′UTR), have not been investigated until now. Here, a series of nucleotides present in...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Li, Zhaolong, Liu, Xin, Wang, Shaohua, Li, Jingliang, Hou, Min, Liu, Guanchen, Zhang, Wenyan, Yu, Xiao-Fang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748407/
https://ncbi.nlm.nih.gov/pubmed/26861413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20839
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