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Effects of the nicotinic α7 receptor partial agonist GTS-21 on NMDA-glutamatergic receptor related deficits in sensorimotor gating and recognition memory in rats

RATIONALE: Disturbances in information processing and cognitive function are key features of schizophrenia. Nicotinic α7 acetylcholine receptors (α7-nAChR) are involved in sensory gating and cognition, thereby representing a viable therapeutic strategy. OBJECTIVES AND METHODS: We investigated the ef...

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Pubblicato in:Psychopharmacology (Berl)
Autori principali: Callahan, Patrick M., Terry, Alvin V., Tehim, Ashok
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748388/
https://ncbi.nlm.nih.gov/pubmed/24595504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3509-2
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