MiR218 Modulates Wnt Signaling in Mouse Cardiac Stem Cells by Promoting Proliferation and Inhibiting Differentiation through a Positive Feedback Loop

MiRNA expression was determined in both proliferating and differentiated cardiac stem cells (CSCs) through a comprehensive miRNA microarray analysis. We selected miR218 for functional follow-up studies to examine its significance in CSCs. First, we observed that the expression of miR218 was altered...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Yongshun, Liu, Jingjin, Cui, Jinjin, Sun, Meng, Du, Wenjuan, Chen, Tao, Ming, Xing, Zhang, Lulu, Tian, Jiangtian, Li, Ji, Yin, Li, Liu, Fang, Pu, Zhongyue, Lv, Bo, Hou, Jingbo, Yu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748271/
https://ncbi.nlm.nih.gov/pubmed/26860887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20968
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