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Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Opiates such as morphine and codeine are mainly obtained by extraction from opium poppies. Fermentative opiate production in microbes has also been investigated, and complete biosynthesis of opiates from a simple carbon source has recently been accomplished in yeast. Here we demonstrate that Escheri...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748248/ https://ncbi.nlm.nih.gov/pubmed/26847395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10390 |
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