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The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates

Although molecular tests for drug-resistant TB perform well on culture isolates, their accuracy using clinical samples, particularly from TB and HIV-endemic settings, requires clarification. The MTBDRplus and MTBDRsl line probe assays were evaluated in 181 sputum samples and 270 isolates from patien...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tomasicchio, Michele, Theron, Grant, Pietersen, Elize, Streicher, Elizabeth, Stanley-Josephs, Danielle, van Helden, Paul, Warren, Rob, Dheda, Keertan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748215/
https://ncbi.nlm.nih.gov/pubmed/26860462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17850
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