Galectin-8 promotes regulatory T cell differentiation by modulating IL-2 and TGFβ signaling

Galectins have emerged as potent immunoregulatory molecules that control chronic inflammation through distinct mechanisms. Galectin-8 (Gal-8), a tandem-repeat type galectin with unique preference for α2,3-sialylated glycans, is ubiquitously expressed, but little is known about its role in T cell dif...

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Bibliographic Details
Published in:Immunol Cell Biol
Main Authors: Sampson, James F., Suryawanshi, Amol, Chen, Wei-Sheng, Rabinovich, Gabriel A., Panjwani, Noorjahan
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747822/
https://ncbi.nlm.nih.gov/pubmed/26282995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.72
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