Protective Effect of HLA-DQB1 Alleles Against Alloimmunization in Patients with Sickle Cell Disease

BACKGROUND: Alloimmunization or the development of alloantibodies to Red Blood Cell (RBC) antigens is considered one of the major complications after RBC transfusions in patients with sickle cell disease (SCD) and can lead to both acute and delayed hemolytic reactions. It has been suggested that pol...

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Veröffentlicht in:Hum Immunol
Hauptverfasser: Tatari-Calderone, Zohreh, Gordish-Dressman, Heather, Fasano, Ross, Riggs, Michael, Fortier, Catherine, Andrew, Campbell, D., Charron, Dominique, Gordeuk, Victor R., Luban, Naomi L.C., Vukmanovic, Stanislav, Tamouza, Ryad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747802/
https://ncbi.nlm.nih.gov/pubmed/26476208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2015.10.010
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