Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient

Compensatory signaling pathways in tumors confer resistance to targeted therapy, but the pathways and their mechanisms of activation remain largely unknown. We describe a procedure for quantitative proteomics and phosphoproteomics on snap-frozen biopsies of hepatocellular carcinoma (HCC) and matched...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Dazert, Eva, Colombi, Marco, Boldanova, Tujana, Moes, Suzette, Adametz, David, Quagliata, Luca, Roth, Volker, Terracciano, Luigi, Heim, Markus H., Jenoe, Paul, Hall, Michael N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747770/
https://ncbi.nlm.nih.gov/pubmed/26787912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523434113
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