Beneficial effects of IL-37 after spinal cord injury in mice

IL-37, a member of the IL-1 family, broadly reduces innate inflammation as well as acquired immunity. Whether the antiinflammatory properties of IL-37 extend to the central nervous system remains unknown, however. In the present study, we subjected mice transgenic for human IL-37 (hIL-37tg) and wild...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Coll-Miró, Marina, Francos-Quijorna, Isaac, Santos-Nogueira, Eva, Torres-Espin, Abel, Bufler, Philip, Dinarello, Charles A., López-Vales, Rubèn
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747716/
https://ncbi.nlm.nih.gov/pubmed/26787859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523212113
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