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Programmable polyproteams built using twin peptide superglues

Programmed connection of amino acids or nucleotides into chains introduced a revolution in control of biological function. Reacting proteins together is more complex because of the number of reactive groups and delicate stability. Here we achieved sequence-programmed irreversible connection of prote...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Veggiani, Gianluca, Nakamura, Tomohiko, Brenner, Michael D., Gayet, Raphaël V., Yan, Jun, Robinson, Carol V., Howarth, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747704/
https://ncbi.nlm.nih.gov/pubmed/26787909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519214113
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