Assessment of the Relation between the Expression of Oxaliplatin Transporters in Colorectal Cancer and Response to FOLFOX-4 Adjuvant Chemotherapy: A Case Control Study

BACKGROUND: Adjuvant chemotherapy for colorectal cancer is mainly based on the combination of 5-fluorouracil, folinic acid and oxaliplatin (FOLFOX-4). The pharmacological target of oxaliplatin remains intracellular and therefore dependent on its entry into cells. The intracellular distribution of ox...

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Udgivet i:PLoS One
Main Authors: Le Roy, Bertrand, Tixier, Lucie, Pereira, Bruno, Sauvanet, Pierre, Buc, Emmanuel, Pétorin, Caroline, Déchelotte, Pierre, Pezet, Denis, Balayssac, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747515/
https://ncbi.nlm.nih.gov/pubmed/26859833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148739
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