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Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p

BACKGROUND: MicroRNAs (miRNAs) regulate gene expression by interfering translation or stability of target transcripts. This interplay between miRNA and their mRNA has been proposed as an important process in cancer development and progression. We have investigated molecular networks impacted by pred...

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Publicat a:PLoS One
Autors principals: Wotschofsky, Zofia, Gummlich, Linda, Liep, Julia, Stephan, Carsten, Kilic, Ergin, Jung, Klaus, Billaud, Jean-Noel, Meyer, Hellmuth-Alexander
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747468/
https://ncbi.nlm.nih.gov/pubmed/26859141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148746
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