CMTM7 knockdown increases tumorigenicity of human non-small cell lung cancer cells and EGFR-AKT signaling by reducing Rab5 activation

The dysregulation of epidermal growth factor receptor (EGFR) signaling has been well documented to contribute to the progression of non-small cell lung cancer (NSCLC), the leading cause of cancer death in the world. EGF-stimulated EGFR activation induces receptor internalization and degradation, whi...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Baocai, Su, Yu, Li, Ting, Yuan, Wanqiong, Mo, Xiaoning, Li, Henan, He, Qihua, Ma, Dalong, Han, Wenling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747392/
https://ncbi.nlm.nih.gov/pubmed/26528697
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