Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice

Ephrin receptor A4 (EphA4) is overexpressed in human pancreatic adenocarcinoma (PDAC) and activate cell growth. Recent studies have identified small molecules that block EphA4. In this study, we investigated the correlation between EphA4 expression and the prognosis of patients with PDAC. We also ex...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Takano, Hironobu, Nakamura, Toru, Tsuchikawa, Takahiro, Kushibiki, Toshihiro, Hontani, Kouji, Inoko, Kazuho, Takahashi, Mizuna, Sato, Shoki, Abe, Hirotake, Takeuchi, Shintaro, Sato, Nagato, Hiraoka, Kei, Nishihara, Hiroshi, Shichinohe, Toshiaki, Hirano, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747390/
https://ncbi.nlm.nih.gov/pubmed/26516928
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