LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer

The Polycomb protein enhancer of zeste homolog 2 (EZH2) is frequently overexpressed in advanced human prostate cancer (PCa), especially in lethal castration-resistant prostate cancer (CRPC). However, the signaling pathways that regulate EZH2 functions in PCa remain incompletely defined. Using EZH2 a...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Wang, Dejie, Ding, Liya, Wang, Liguo, Zhao, Yu, Sun, Zhifu, Karnes, R. Jeffrey, Zhang, Jun, Huang, Haojie
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747388/
https://ncbi.nlm.nih.gov/pubmed/26516927
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