MicroRNA-29B (mir-29b) regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3

Epithelial ovarian cancer (EOC) is the most lethal and aggressive gynecological malignancy, and abnormal cellular metabolism significantly contributes to cancer onset and progression. Here, we report that miR-29b negatively regulates AKT2/AKT3 expression, causing HK2/PKM2 downregulation and leading...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Teng, Yue, Zhang, Yan, Qu, Kai, Yang, Xinyuan, Fu, Jing, Chen, Wei, Li, Xu
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747369/
https://ncbi.nlm.nih.gov/pubmed/26512921
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