MicroRNA-29B (mir-29b) regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3

Epithelial ovarian cancer (EOC) is the most lethal and aggressive gynecological malignancy, and abnormal cellular metabolism significantly contributes to cancer onset and progression. Here, we report that miR-29b negatively regulates AKT2/AKT3 expression, causing HK2/PKM2 downregulation and leading...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Teng, Yue, Zhang, Yan, Qu, Kai, Yang, Xinyuan, Fu, Jing, Chen, Wei, Li, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747369/
https://ncbi.nlm.nih.gov/pubmed/26512921
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