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Molecular mechanisms of cisplatin cytotoxicity in acute promyelocytic leukemia cells

Cis-diamminedichloroplatinum (II) (cisplatin) is a widely used anti-tumor drug for the treatment of a broad range of human malignancies with successful therapeutic outcomes for head and neck, ovarian, and testicular cancers. It has been found to inhibit cell cycle progression and to induce oxidative...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kumar, Sanjay, Tchounwou, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747365/
https://ncbi.nlm.nih.gov/pubmed/26486083
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