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Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

DNA replication is a highly coordinated process that is initiated at multiple replication origins in eukaryotes. These origins are bound by the origin recognition complex (ORC), which subsequently recruits the Mcm2-7 replicative helicase in a Cdt1/Cdc6-dependent manner. In budding yeast, two essenti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kliszczak, Maciej, Sedlackova, Hana, Pitchai, Ganesha P., Streicher, Werner W., Krejci, Lumir, Hickson, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747346/
https://ncbi.nlm.nih.gov/pubmed/26588054
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