Palbociclib inhibits epithelial-mesenchymal transition and metastasis in breast cancer via c-Jun/COX-2 signaling pathway

Palbociclib, a highly selective CDK4/6 inhibitor, has been shown to be a novel anti-tumor agent that suppresses breast cancer cell proliferation. However, its anti-metastasis activity remains controversial. In the present study, we evaluated whether palbociclib prevented breast cancer cell metastasi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qin, Ge, Xu, Fei, Qin, Tao, Zheng, Qiufan, Shi, Dingbo, Xia, Wen, Tian, Yun, Tang, Yanlai, Wang, Jingshu, Xiao, Xiangshen, Deng, Wuguo, Wang, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747189/
https://ncbi.nlm.nih.gov/pubmed/26540629
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