Efficacy of Sustained-Release Buprenorphine in an Experimental Laparotomy Model in Female Mice

Mice purportedly require dosing with the opioid buprenorphine (Bup-HCl) at least every 8 to 12 h to maintain an adequate plane of analgesia. Here we used an experimental laparotomy model to determine the clinical efficacy of sustained-release formulations of buprenorphine (Bup-SR) after surgery in m...

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Detalhes bibliográficos
Publicado no:J Am Assoc Lab Anim Sci
Main Authors: Kendall, Lon V, Wegenast, Daniel J, Smith, Brian J, Dorsey, Kathryn M, Kang, Sooah, Lee, Na Young, Hess, Ann M
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2016
Assuntos:
Anesthesia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747013/
https://ncbi.nlm.nih.gov/pubmed/26817982
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