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Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study

INTRODUCTION: Deposition of abnormally phosphorylated tau (phospho-tau) occurs in Alzheimer’sdisease but also with brain ageing. The Braak staging scheme focused on neurofibrillary tangles, butabundant p-tau is also present in neuropil threads, and a recent scheme has been proposed by theBrainNet Eu...

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Bibliografski detalji
Izdano u:Acta Neuropathol Commun
Glavni autori: Wharton, Stephen B., Minett, Thais, Drew, David, Forster, Gillian, Matthews, Fiona, Brayne, Carol, Ince, Paul G.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746919/
https://ncbi.nlm.nih.gov/pubmed/26857919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0275-x
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