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Scalable linkage-disequilibrium-based selective sweep detection: a performance guide

BACKGROUND: Linkage disequilibrium is defined as the non-random associations of alleles at different loci, and it occurs when genotypes at the two loci depend on each other. The model of genetic hitchhiking predicts that strong positive selection affects the patterns of linkage disequilibrium around...

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Bibliographic Details
Published in:Gigascience
Main Authors: Alachiotis, Nikolaos, Pavlidis, Pavlos
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746822/
https://ncbi.nlm.nih.gov/pubmed/26862394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13742-016-0114-9
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