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Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia – can findings from animal models be translated to humans?

BACKGROUND: Cachexia is a multi-factorial, systemic syndrome that especially affects patients with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival and quality of life. The most important clinical feature of cachexia is the excessive wasting of skeletal muscle...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Mueller, Tara C., Bachmann, Jeannine, Prokopchuk, Olga, Friess, Helmut, Martignoni, Marc E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746781/
https://ncbi.nlm.nih.gov/pubmed/26856534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2121-8
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