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The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin

Differentiation of inflammatory macrophages from monocytes is characterized by an orderly integration of epigenetic and transcriptional regulatory mechanisms guided by lineage-determining transcription factors such as PU.1. Further activation of macrophages leads to a stimulus- or microenvironment-s...

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Dettagli Bibliografici
Pubblicato in:Cell Res
Autori principali: Schmidt, Susanne V, Krebs, Wolfgang, Ulas, Thomas, Xue, Jia, Baßler, Kevin, Günther, Patrick, Hardt, Anna-Lena, Schultze, Hartmut, Sander, Jil, Klee, Kathrin, Theis, Heidi, Kraut, Michael, Beyer, Marc, Schultze, Joachim L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746609/
https://ncbi.nlm.nih.gov/pubmed/26729620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.1
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