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The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin

Differentiation of inflammatory macrophages from monocytes is characterized by an orderly integration of epigenetic and transcriptional regulatory mechanisms guided by lineage-determining transcription factors such as PU.1. Further activation of macrophages leads to a stimulus- or microenvironment-s...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Schmidt, Susanne V, Krebs, Wolfgang, Ulas, Thomas, Xue, Jia, Baßler, Kevin, Günther, Patrick, Hardt, Anna-Lena, Schultze, Hartmut, Sander, Jil, Klee, Kathrin, Theis, Heidi, Kraut, Michael, Beyer, Marc, Schultze, Joachim L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746609/
https://ncbi.nlm.nih.gov/pubmed/26729620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.1
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