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The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness
Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments is an emerging...
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| Veröffentlicht in: | Pharmacogenomics J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746489/ https://ncbi.nlm.nih.gov/pubmed/25869012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.26 |
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