Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

The GluD2 receptor is a fundamental component of postsynaptic sites in Purkinje neurons, and is required for normal cerebellar function. GluD2 and the closely related GluD1 are classified as members of the ionotropic glutamate receptor (iGluR) superfamily on the basis of sequence similarity, but do...

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Veröffentlicht in:Mol Pharmacol
Hauptverfasser: Kristensen, Anders S., Hansen, Kasper B., Naur, Peter, Olsen, Lars, Kurtkaya, Natalie L., Dravid, Shashank M., Kvist, Trine, Yi, Feng, Pøhlsgaard, Jacob, Clausen, Rasmus P., Gajhede, Michael, Kastrup, Jette S., Traynelis, Stephen F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746485/
https://ncbi.nlm.nih.gov/pubmed/26661043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.100909
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