Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis

Objective. RA predominantly affects post-menopausal women and is strongly associated with development of generalised osteoporosis. To find treatments that target both joint manifestations and osteoporosis in RA is desirable. The third generation of selective oestrogen receptor modulators (SERMs) [la...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Rheumatology (Oxford)
Main Authors: Andersson, Annica, Bernardi, Angelina I., Stubelius, Alexandra, Nurkkala-Karlsson, Merja, Ohlsson, Claes, Carlsten, Hans, Islander, Ulrika
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Basic Science
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746431/
https://ncbi.nlm.nih.gov/pubmed/26424839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kev355
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