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Gene, environment, microbiome and mucosal immune tolerance in rheumatoid arthritis

RA is a complex multifactorial chronic disease that transitions through several stages. Multiple studies now support that there is a prolonged phase in early RA development during which there is serum elevation of RA-related autoantibodies including RF and ACPAs in the absence of clinically evident...

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Bibliographic Details
Published in:Rheumatology (Oxford)
Main Authors: Catrina, Anca I., Deane, Kevin D., Scher, Jose U.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746430/
https://ncbi.nlm.nih.gov/pubmed/25539828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keu469
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