Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans

Platelets play an essential role in hemostasis and thrombosis. We performed a genome-wide association study of platelet count in 12,491 participants of the Hispanic Community Health Study/Study of Latinos by using a mixed-model method that accounts for admixture and family relationships. We discover...

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Vydáno v:Am J Hum Genet
Hlavní autoři: Schick, Ursula M., Jain, Deepti, Hodonsky, Chani J., Morrison, Jean V., Davis, James P., Brown, Lisa, Sofer, Tamar, Conomos, Matthew P., Schurmann, Claudia, McHugh, Caitlin P., Nelson, Sarah C., Vadlamudi, Swarooparani, Stilp, Adrienne, Plantinga, Anna, Baier, Leslie, Bien, Stephanie A., Gogarten, Stephanie M., Laurie, Cecelia A., Taylor, Kent D., Liu, Yongmei, Auer, Paul L., Franceschini, Nora, Szpiro, Adam, Rice, Ken, Kerr, Kathleen F., Rotter, Jerome I., Hanson, Robert L., Papanicolaou, George, Rich, Stephen S., Loos, Ruth J.F., Browning, Brian L., Browning, Sharon R., Weir, Bruce S., Laurie, Cathy C., Mohlke, Karen L., North, Kari E., Thornton, Timothy A., Reiner, Alex P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746331/
https://ncbi.nlm.nih.gov/pubmed/26805783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.12.003
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