Functional Analysis of the Citrate Activator CitO from Enterococcus faecalis Implicates a Divalent Metal in Ligand Binding

The regulator of citrate metabolism, CitO, from Enterococcus faecalis belongs to the FCD family within the GntR superfamily. In the presence of citrate, CitO binds to cis-acting sequences located upstream of the cit promoters inducing the expression of genes involved in citrate utilization. The quan...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Blancato, Víctor S., Pagliai, Fernando A., Magni, Christian, Gonzalez, Claudio F., Lorca, Graciela L.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746285/
https://ncbi.nlm.nih.gov/pubmed/26903980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00101
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