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Controversies in Establishing Biosimilarity: Extrapolation of Indications and Global Labeling Practices

The principles of establishing biosimilarity are to demonstrate structural and functional similarity to a reference product using the most discriminatory analytical methods. There is still considerable controversy on the scientific basis for extrapolation of indications for biosimilars, which has be...

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Bibliografiske detaljer
Udgivet i:BioDrugs
Main Authors: Ebbers, Hans C., Chamberlain, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746210/
https://ncbi.nlm.nih.gov/pubmed/26758077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-015-0154-1
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