Vaccination with the Surface Proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans Induces Antibodies but Fails to Provide Protection against Buruli Ulcer

BACKGROUND: Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African countries. M. ulcerans produces a cytotoxic macrolide exotoxin called mycolactone, which causes ext...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Bolz, Miriam, Bénard, Angèle, Dreyer, Anita M., Kerber, Sarah, Vettiger, Andrea, Oehlmann, Wulf, Singh, Mahavir, Duthie, Malcolm S., Pluschke, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746116/
https://ncbi.nlm.nih.gov/pubmed/26849213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004431
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