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Generating Peripheral Blood Derived Lymphocytes Reacting Against Autologous Primary AML Blasts

Expanding on our prior studies with cord blood T-cells, we hypothesized that primary AML-reactive autologous T-cells could be generated ex vivo under immunomodulatory conditions. We purified AML and T-cells from 8 newly diagnosed high-risk patients. After 2 weeks expansion, T-cells were stimulated w...

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Detalles Bibliográficos
Publicado en:J Immunother
Main Authors: Mehta, Rohtesh S., Chen, Xiaohua, Antony, Jeyaraj, Boyiadzis, Michael, Szabolcs, Paul
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746019/
https://ncbi.nlm.nih.gov/pubmed/26849076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000107
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