Curcumin enhances the cytogenotoxic effect of etoposide in leukemia cells through induction of reactive oxygen species

Curcumin may exert a more selective cytotoxic effect in tumor cells with elevated levels of free radicals. Here, we investigated whether curcumin can modulate etoposide action in myeloid leukemia cells and in normal cells of hematopoietic origin. HL-60 cell line, normal myeloid progenitor cluster of...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Papież, Monika A, Krzyściak, Wirginia, Szade, Krzysztof, Bukowska-Straková, Karolina, Kozakowska, Magdalena, Hajduk, Karolina, Bystrowska, Beata, Dulak, Jozef, Jozkowicz, Alicja
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745860/
https://ncbi.nlm.nih.gov/pubmed/26893544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S92687
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