Randomized clinical trial: pharmacokinetics and safety of multimatrix mesalamine for treatment of pediatric ulcerative colitis

BACKGROUND: Limited data are available on mesalamine (5-aminosalicylic acid; 5-ASA) use in pediatric ulcerative colitis (UC). AIM: To evaluate pharmacokinetic and safety profiles of 5-ASA and metabolite acetyl-5-ASA (Ac-5-ASA) after once-daily, oral administration of multimatrix mesalamine to childr...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Cuffari, Carmen, Pierce, David, Korczowski, Bartosz, Fyderek, Krzysztof, Van Heusen, Heather, Hossack, Stuart, Wan, Hong, Edwards, Alena YZ, Martin, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745832/
https://ncbi.nlm.nih.gov/pubmed/26893546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S95316
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