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Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control
Genome-wide association studies (GWAS) have identified over 40 type 1 diabetes risk loci. The clinical impact of these loci on β-cell function during disease progression is unknown. We aimed at testing whether a genetic risk score could predict glycemic control and residual β-cell function in type 1...
Zapisane w:
Wydane w: | J Diabetes Res |
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Główni autorzy: | , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Hindawi Publishing Corporation
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4745814/ https://ncbi.nlm.nih.gov/pubmed/26904692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9570424 |
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