Vaccinia-related kinase 1 promotes hepatocellular carcinoma by controlling the levels of cell cycle regulators associated with G1/S transition

We identified the specific role of vaccinia-related kinase 1 (VRK1) in the progression of hepatocellular carcinoma (HCC) and evaluated its therapeutic and prognostic potential. VRK1 levels were significantly higher in HCC cell lines than a normal hepatic cell line, and were higher in HCC than non-tu...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lee, Namgyu, Kwon, Jung-Hee, Kim, Young Bae, Kim, Seong-Hoon, Park, Sung Jin, Xu, Weiguang, Jung, Hoe-Yune, Kim, Kyong-Tai, Wang, Hee Jung, Choi, Kwan Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745786/
https://ncbi.nlm.nih.gov/pubmed/26375549
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