Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

The mechanisms of cisplatin resistance, one of the major limitations of current chemotherapy, has only partially been described. We previously demonstrated that cisplatin-resistant ovarian cancer cells (C13), are characterized by reduced mitochondrial activity and higher glucose-dependency when comp...

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Publicat a:Oncotarget
Autors principals: Catanzaro, Daniela, Gaude, Edoardo, Orso, Genny, Giordano, Carla, Guzzo, Giulia, Rasola, Andrea, Ragazzi, Eugenio, Caparrotta, Laura, Frezza, Christian, Montopoli, Monica
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745784/
https://ncbi.nlm.nih.gov/pubmed/26337086
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