Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention

Cancer-associated fibroblasts (CAFs) constitute an important part of the tumor microenvironment and promote invasion via paracrine functions and physical impact on the tumor. Although the importance of including CAFs into three-dimensional (3D) cell cultures has been acknowledged, computational supp...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Åkerfelt, Malin, Bayramoglu, Neslihan, Robinson, Sean, Toriseva, Mervi, Schukov, Hannu-Pekka, Härmä, Ville, Virtanen, Johannes, Sormunen, Raija, Kaakinen, Mika, Kannala, Juho, Eklund, Lauri, Heikkilä, Janne, Nees, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745780/
https://ncbi.nlm.nih.gov/pubmed/26375443
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