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Aberrant reduction of telomere repetitive sequences in plasma cell-free DNA for early breast cancer detection

Excessive telomere shortening is observed in breast cancer lesions when compared to adjacent non-cancerous tissues, suggesting that telomere length may represent a key biomarker for early cancer detection. Because tumor-derived, cell-free DNA (cfDNA) is often released from cancer cells and circulate...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Wu, Xi, Tanaka, Hiromi
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745763/
https://ncbi.nlm.nih.gov/pubmed/26356673
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