Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells

Tumor-associated macrophages (TAMs) play an important role in cancer cell survival, however, the mechanism of which remains elusive. In this study, we found that COX-2 was abundantly expressed in breast TAMs, which was correlated to poor prognosis in breast cancer patients. Ectopic over-expression o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Hongzhong, Yang, Bing, Huang, Jing, Lin, Yong, Xiang, Tingxiu, Wan, Jingyuan, Li, Hongyuan, Chouaib, Salem, Ren, Guosheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745752/
https://ncbi.nlm.nih.gov/pubmed/26359357
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