The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop

Deregulation of the pituitary tumor transforming gene (PTTG1), a newly discovered oncogene, is a hallmark of various malignancies, including pituitary tumors. However, the mechanisms regulating PTTG1 expression are still needed to be explored. MicroRNAs (miRNAs) are a novel class of small RNA molecu...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Liang, Hai-qian, Wang, Ren-jie, Diao, Cai-feng, Li, Jian-wei, Su, Jing-liang, Zhang, Sai
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745736/
https://ncbi.nlm.nih.gov/pubmed/26320179
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