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A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation

A new generation of anticancer therapeutics called target drugs has quickly developed in the 21(st) century. These drugs are tailored to inhibit cancer cell growth, proliferation, and viability by specific interactions with one or a few target proteins. However, despite formally known molecular targ...

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Pubblicato in:Oncotarget
Autori principali: Artemov, Artem, Aliper, Alexander, Korzinkin, Michael, Lezhnina, Ksenia, Jellen, Leslie, Zhukov, Nikolay, Roumiantsev, Sergey, Gaifullin, Nurshat, Zhavoronkov, Alex, Borisov, Nicolas, Buzdin, Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745731/
https://ncbi.nlm.nih.gov/pubmed/26320181
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